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MOTS-C (Mitochondrial ORF of the 12S rRNA type-c) is a small peptide produced from mitochondrial DNA, giving it a distinctive place among bioactive peptides. Research suggests it impacts AMPK and other nutrient-sensing networks that control how cells respond to energy shortages and metabolic stress.

In wellness and performance clinics, MOTS-C is often used in programs that emphasize exercise capacity, metabolic flexibility, and longevity. It may be incorporated into seasonal “metabolic reset” protocols or combined with lifestyle interventions that stress movement, fasting-mimicking strategies, and nutrient timing.

Individuals drawn to MOTS-C typically value both performance and healthy aging, looking to support how their cells adapt to stress and use fuel over the long term. It is a natural companion to NAD+, mitochondrial antioxidants, and other energy-focused compounds.

All statements are for informational purposes only. MOTS-C is not intended to diagnose, treat, cure, or prevent any disease and should only be utilized under professional supervision.

   •    Mitochondrial-derived peptide supporting nutrient-sensing and metabolic adaptation pathways.

   •    Store refrigerated; protect from light; use within recommended time after reconstitution.

   •    Intended for use in metabolic flexibility and longevity-focused wellness programs.

   •    Ships in protective, insulated packaging as needed.

   •    Stable during standard shipping; refrigerate upon arrival.

   •    Avoid exposure to high heat or freezing of reconstituted solutions.

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